Premium Phosphosite-Specific 7TM Antibodies
Novel Tools for Your GPCR Research
Select Your Country of Delivery below

GPR88 Receptor Antibodies

Close filters
No results were found for the filter!
NEW
Validation of the GPR88 Receptor in transfected HEK293 cells
GPR88 (non-phospho), G protein-coupled...
The non-phospho-GPR88 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human GPR88. It can be used to detect total GPR3 receptors in Western blots independent of phosphorylation. The GPR88 antibody...
CHF400.00 *
Details

GPR88 (G Protein-Coupled Receptor 88) is an orphan GPCR with no confirmed endogenous ligand, but it is known to play a key role in modulating neurotransmission and behavioral regulation. It primarily signals through Gi/o proteins, inhibiting intracellular cAMP production. GPR88 is highly and selectively expressed in the central nervous system, particularly in the striatum, nucleus accumbens, and cortex—regions involved in motor control, reward processing, and emotional regulation. GPR88 is considered a promising pharmacological target for neuropsychiatric and neurological disorders, including schizophrenia, Parkinson’s disease, addiction, and depression. Preclinical studies show that modulating GPR88 activity can influence dopaminergic and glutamatergic signaling. For more information on GPR88 pharmacology please refer to the IUPHAR database. For further reading refer to:

Davenport AP, Alexander SP, Sharman JL, Pawson AJ, Benson HE, Monaghan AE, Liew WC, Mpamhanga CP, Bonner TI, Neubig RR, Pin JP, Spedding M, Harmar AJ. International Union of Basic and Clinical Pharmacology. LXXXVIII. G protein-coupled receptor list: recommendations for new pairings with cognate ligands. Pharmacol Rev. 2013 May 17;65(3):967-86. doi: 10.1124/pr.112.007179. PMID: 23686350; PMCID: PMC3698937.

Alexander SP, Battey J, Benson HE, Benya RV, Bonner TI, Davenport AP, Dhanachandra Singh K, Eguchi S, Harmar A, Holliday N, Jensen RT, Karnik S, Kostenis E, Liew WC, Monaghan AE, Mpamhanga C, Neubig R, Pawson AJ, Pin JP, Sharman JL, Spedding M, Spindel E, Stoddart L, Storjohann L, Thomas WG, Tirupula K, Vanderheyden P. Class A Orphans in GtoPdb v.2023.1. IUPHAR/BPS Guide to Pharmacology CITE. 2023; 2023(1). Available from: https://doi.org/10.2218/gtopdb/F16/2023.1.

GPR88 (G Protein-Coupled Receptor 88) is an orphan GPCR with no confirmed endogenous ligand, but it is known to play a key role in modulating neurotransmission and behavioral regulation. It... read more »
Close window
GPR88 Receptor Antibodies

GPR88 (G Protein-Coupled Receptor 88) is an orphan GPCR with no confirmed endogenous ligand, but it is known to play a key role in modulating neurotransmission and behavioral regulation. It primarily signals through Gi/o proteins, inhibiting intracellular cAMP production. GPR88 is highly and selectively expressed in the central nervous system, particularly in the striatum, nucleus accumbens, and cortex—regions involved in motor control, reward processing, and emotional regulation. GPR88 is considered a promising pharmacological target for neuropsychiatric and neurological disorders, including schizophrenia, Parkinson’s disease, addiction, and depression. Preclinical studies show that modulating GPR88 activity can influence dopaminergic and glutamatergic signaling. For more information on GPR88 pharmacology please refer to the IUPHAR database. For further reading refer to:

Davenport AP, Alexander SP, Sharman JL, Pawson AJ, Benson HE, Monaghan AE, Liew WC, Mpamhanga CP, Bonner TI, Neubig RR, Pin JP, Spedding M, Harmar AJ. International Union of Basic and Clinical Pharmacology. LXXXVIII. G protein-coupled receptor list: recommendations for new pairings with cognate ligands. Pharmacol Rev. 2013 May 17;65(3):967-86. doi: 10.1124/pr.112.007179. PMID: 23686350; PMCID: PMC3698937.

Alexander SP, Battey J, Benson HE, Benya RV, Bonner TI, Davenport AP, Dhanachandra Singh K, Eguchi S, Harmar A, Holliday N, Jensen RT, Karnik S, Kostenis E, Liew WC, Monaghan AE, Mpamhanga C, Neubig R, Pawson AJ, Pin JP, Sharman JL, Spedding M, Spindel E, Stoddart L, Storjohann L, Thomas WG, Tirupula K, Vanderheyden P. Class A Orphans in GtoPdb v.2023.1. IUPHAR/BPS Guide to Pharmacology CITE. 2023; 2023(1). Available from: https://doi.org/10.2218/gtopdb/F16/2023.1.

Recently viewed