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Oxoeicosanoid Receptor Antibodies

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Validation of the OXE Receptor in transfected HEK293 cells.
OXER (non-phospho), Oxoeicosanoid Receptor...
The non-phospho-OXE receptor antibody is directed against the distal end of the carboxyl-terminal tail of human OXER. It can be used to detect total OXE receptors in Western blots independent of phosphorylation. The OXER antibody can...
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OXER (Oxoeicosanoid Receptor) is a G protein-coupled receptor (GPCR) that primarily binds to 5-oxo-eicosatetraenoic acid (5-oxo-ETE), a potent lipid mediator derived from arachidonic acid. Activation of OXER1 leads to the mobilization and activation of immune cells, especially those involved in inflammatory responses. OXER is mainly expressed in myeloid lineage cells, including eosinophils, neutrophils, monocytes, and certain types of macrophages. It is also found in some epithelial and cancer cells, particularly in the prostate, lung, and colon. OXER is considered a promising pharmacological target due to its role in mediating inflammatory responses and its involvement in diseases such as asthma, allergic inflammation, and certain cancers. For more information on BLT2 pharmacology please refer to the IUPHAR database. For further reading refer to:

Bäck M, Dahlén SE, Drazen JM, Evans JF, Serhan CN, Shimizu T, Yokomizo T, Rovati GE. International Union of Basic and Clinical Pharmacology. LXXXIV: leukotriene receptor nomenclature, distribution, and pathophysiological functions. Pharmacol Rev. 2011 Sep;63(3):539-84. doi: 10.1124/pr.110.004184. PMID: 21771892.

Bäck M, Powell WS, Dahlén SE, Drazen JM, Evans JF, Serhan CN, Shimizu T, Yokomizo T, Rovati GE. Update on leukotriene, lipoxin and oxoeicosanoid receptors: IUPHAR Review 7. Br J Pharmacol. 2014 Aug;171(15):3551-74. doi: 10.1111/bph.12665. Epub 2014 Jul 12. PMID: 24588652; PMCID: PMC4128057.

OXER (Oxoeicosanoid Receptor) is a G protein-coupled receptor (GPCR) that primarily binds to 5-oxo-eicosatetraenoic acid (5-oxo-ETE), a potent lipid mediator derived from arachidonic acid.... read more »
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Oxoeicosanoid Receptor Antibodies

OXER (Oxoeicosanoid Receptor) is a G protein-coupled receptor (GPCR) that primarily binds to 5-oxo-eicosatetraenoic acid (5-oxo-ETE), a potent lipid mediator derived from arachidonic acid. Activation of OXER1 leads to the mobilization and activation of immune cells, especially those involved in inflammatory responses. OXER is mainly expressed in myeloid lineage cells, including eosinophils, neutrophils, monocytes, and certain types of macrophages. It is also found in some epithelial and cancer cells, particularly in the prostate, lung, and colon. OXER is considered a promising pharmacological target due to its role in mediating inflammatory responses and its involvement in diseases such as asthma, allergic inflammation, and certain cancers. For more information on BLT2 pharmacology please refer to the IUPHAR database. For further reading refer to:

Bäck M, Dahlén SE, Drazen JM, Evans JF, Serhan CN, Shimizu T, Yokomizo T, Rovati GE. International Union of Basic and Clinical Pharmacology. LXXXIV: leukotriene receptor nomenclature, distribution, and pathophysiological functions. Pharmacol Rev. 2011 Sep;63(3):539-84. doi: 10.1124/pr.110.004184. PMID: 21771892.

Bäck M, Powell WS, Dahlén SE, Drazen JM, Evans JF, Serhan CN, Shimizu T, Yokomizo T, Rovati GE. Update on leukotriene, lipoxin and oxoeicosanoid receptors: IUPHAR Review 7. Br J Pharmacol. 2014 Aug;171(15):3551-74. doi: 10.1111/bph.12665. Epub 2014 Jul 12. PMID: 24588652; PMCID: PMC4128057.

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