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Orphan Receptor Antibodies

The sequencing of the human genome has allowed NC-IUPHAR to catalog all of the human gene sequences potentially encoding GPCRs, excluding sensory receptors. In addition to established transmitter systems, the classification in the Guide to PHARMACOLOGY also includes ‘orphan’ GPCRs where the endogenous ligand(s) is not known. Considerable progress has been made in screening artificially expressed receptors to identify the cognate endogenous ligand.

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OR51E1 (IHC-Grade), OR51E1 Antibody
OR51E1 (IHC-Grade), OR51E1 Antibody
The non-phospho-OR51E1 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human OR51E1. It can be used to detect total OR51E1 receptors in Western blots independent of phosphorylation. The OR51E1...
CHF400.00 *
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NEW
Validation of the OR51E1 Receptor in transfected HEK293 cells.
OR51E1 (non-phospho), OR51E1 Antibody
The non-phospho-OR51E1 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human OR51E1. It can be used to detect total OR51E1 receptors in Western blots independent of phosphorylation. The OR51E1...
CHF400.00 *
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Validation of the GPR162 Receptor in transfected HEK293 cells.
GPR162 (non-phospho), G protein-coupled...
The non-phospho-GPR162 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human GPR162. It can be used to detect total GPR162 receptors in Western blots independent of phosphorylation. The GPR162...
CHF400.00 *
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GPR162 (IHC-Grade), G protein-coupled Receptor 162 Antibody
GPR162 (IHC-Grade), G protein-coupled Receptor...
The non-phospho-GPR162 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human GPR162. It can be used to detect total GPR162 receptors in Western blots independent of phosphorylation. The GPR162...
CHF400.00 *
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Validation of the GPR150 Receptor in transfected HEK293 cells.
GPR150 (non-phospho), G protein-coupled...
The non-phospho-GPR150 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human GPR150. It can be used to detect total GPR150 receptors in Western blots independent of phosphorylation. The GPR150...
CHF400.00 *
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GPR150 (IHC-Grade), G protein-coupled Receptor 150 Antibody
GPR150 (IHC-Grade), G protein-coupled Receptor...
The non-phospho-GPR150 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human GPR150. It can be used to detect total GPR150 receptors in Western blots independent of phosphorylation. The GPR150...
CHF400.00 *
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NEW
Validation of the GPR149 Receptor in transfected HEK293 cells
GPR149 (non-phospho), G protein-coupled...
The non-phospho-GPR149 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human GPR149. It can be used to detect total GPR149 receptors in Western blots independent of phosphorylation. The GPR149...
CHF400.00 *
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GPR149 (IHC-Grade), G protein-coupled Receptor 149 Antibody
GPR149 (IHC-Grade), G protein-coupled Receptor...
The non-phospho-GPR149 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human GPR149. It can be used to detect total GPR149 receptors in Western blots independent of phosphorylation. The GPR149...
CHF400.00 *
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GPR148 (non-phospho), G protein-coupled Receptor 148 Antibody
GPR148 (non-phospho), G protein-coupled...
The non-phospho-GPR148 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human GPR148. It can be used to detect total GPR148 receptors in Western blots independent of phosphorylation. The GPR148...
CHF400.00 *
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GPR148 (IHC-Grade), G protein-coupled Receptor 148 Antibody
GPR148 (IHC-Grade), G protein-coupled Receptor...
The non-phospho-GPR148 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human GPR148. It can be used to detect total GPR148 receptors in Western blots independent of phosphorylation. The GPR148...
CHF400.00 *
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Validation of the GPR85 Receptor in transfected HEK293 cells.
GPR85 (non-phospho), G protein-coupled Receptor...
The non-phospho-GPR85 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human GPR85. It can be used to detect total GPR85 receptors in Western blots independent of phosphorylation. The GPR85 antibody...
CHF400.00 *
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GPR85 (IHC-Grade), G protein-coupled Receptor 85 Antibody
GPR85 (IHC-Grade), G protein-coupled Receptor...
The non-phospho-GPR85 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human GPR85. It can be used to detect total GPR85 receptors in Western blots independent of phosphorylation. The GPR85 antibody...
CHF400.00 *
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Serine422/Serine423 phosphorylation of the G-protein coupled Receptor 75
pS422/pS423-GPR75 (phospho-GPR75 Antibody)
Serine422/Serine423 (S422/S423) is a major phosphorylation site of the human GPR75 receptor. The pS422/pS423-GPR75 antibody detects GRK-mediated constitutive phosphorylation as well as PKC-mediated phosphorylation of GPR75 when expressed...
CHF400.00 *
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Threonine427/Serine429 phosphorylation of the G-protein coupled Receptor 75.
pT427/pS429-GPR75 (phospho-GPR75 Antibody)
Threonine427/Serine429 (T427/S429) is a major phosphorylation site of the human GPR75 receptor. The pT427/pS429-GPR75 antibody detects GRK-mediated constitutive phosphorylation of GPR75 when expressed in HEK293 cells.
CHF400.00 *
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NEW
Immunohistochemical identification of Threonine 427/Serine429 phosphorylation of G-protein coupled Receptor 75 in mouse brain
pT427/pS429-GPR75 (IHC-grade phospho-GPR75...
Threonine427/Serine429 (T427/S429) is a major phosphorylation site of the human GPR75 receptor. The pT427/pS429-GPR75 antibody detects GRK-mediated constitutive phosphorylation of GPR75 when expressed in HEK293 cells.
CHF600.00 *
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NEW
Validation of the GPR75 Receptor in transfected HEK293 cells.
GPR75 (non-phospho), G protein-coupled...
The non-phospho-GPR75 receptor antibody is directed against the distal end of the carboxyl-terminal tail of human GPR75. It can be used to detect total GPR75 receptors in Western blots independent of phosphorylation. The GPR75 antibody...
CHF400.00 *
Details
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For more information on orphan receptor pharmacology please refer to the IUPHAR database. For further reading refer to:

Davenport AP, Alexander SP, Sharman JL, Pawson AJ, Benson HE, Monaghan AE, Liew WC, Mpamhanga CP, Bonner TI, Neubig RR, Pin JP, Spedding M, Harmar AJ. International Union of Basic and Clinical Pharmacology. LXXXVIII. G protein-coupled receptor list: recommendations for new pairings with cognate ligands. Pharmacol Rev. 2013 May 17;65(3):967-86. doi: 10.1124/pr.112.007179. PMID: 23686350; PMCID: PMC3698937.

For more information on orphan receptor pharmacology please refer to the  IUPHAR  database. For further reading refer to: Davenport AP, Alexander SP, Sharman JL, Pawson AJ, Benson HE,... read more »
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Orphan Receptor Antibodies

For more information on orphan receptor pharmacology please refer to the IUPHAR database. For further reading refer to:

Davenport AP, Alexander SP, Sharman JL, Pawson AJ, Benson HE, Monaghan AE, Liew WC, Mpamhanga CP, Bonner TI, Neubig RR, Pin JP, Spedding M, Harmar AJ. International Union of Basic and Clinical Pharmacology. LXXXVIII. G protein-coupled receptor list: recommendations for new pairings with cognate ligands. Pharmacol Rev. 2013 May 17;65(3):967-86. doi: 10.1124/pr.112.007179. PMID: 23686350; PMCID: PMC3698937.

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